Triplex-Inspector: an analysis tool for triplex-mediated targeting of genomic loci
نویسندگان
چکیده
SUMMARY At the heart of many modern biotechnological and therapeutic applications lies the need to target specific genomic loci with pinpoint accuracy. Although landmark experiments demonstrate technological maturity in manufacturing and delivering genetic material, the genomic sequence analysis to find suitable targets lags behind. We provide a computational aid for the sophisticated design of sequence-specific ligands and selection of appropriate targets, taking gene location and genomic architecture into account. AVAILABILITY Source code and binaries are downloadable from www.bioinformatics.org.au/triplexator/inspector. CONTACT [email protected] SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.
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عنوان ژورنال:
- Bioinformatics
دوره 29 15 شماره
صفحات -
تاریخ انتشار 2013